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For Translational Researchers

60\u201380% of your project
time is data wrangling.

OpenBio gives you a normalized, species-agnostic evidence substrate so you can stop building pipelines and start doing science.

Cross-Species Cohort Query
// Query across all 5 species
const cohort = await openBio.queryCohort({
  assertionType: 'variant_call',
  species: 'all',
  trustLayer: 'source_fact'
})}

// → 5 species · 247 variant calls · same schema
60\u201380%of research project time spent on data wrangling
  • Every species, a different schema

    FHIR for humans, DICOM for imaging, GenBank for sequences — no unified data model.

  • Provenance is manual and fragile

    Derived facts overwrite source data. Three months later no one knows where a result came from.

  • Multi-site ETL takes months

    Harmonizing data across institutions requires 6–12 months of custom engineering before analysis can begin.

One Schema. Five Species.

Stop building pipelines. Start doing science.

Species-Agnostic Schema

The same EvidenceAssertion model covers human, canine, primate, cell line, and microbe. Species is metadata, not architecture.

Standard Terminology Built In

LOINC, SNOMED, NCBI taxonomy, and gene ontology are normalized at ingestion — not bolted on later.

Provenance Chains

Every derived fact traces back to source data. No black boxes — every inference knows its parents.

Cohort Queries

Query across subjects by species, assertion type, or trust layer. Compare human and canine oncology cohorts in a single call.

James (NSCLC, human) and Luna (hip dysplasia, canine).
Same schema. Different species.

Human

James Morrison, 58

Homo sapiens \u00b7 TAX_9606

assertion_type:
variant_call
trust_layer:
source_fact
assertions:
847
sources:
6

Canine

Luna, 7yr Golden Retriever

Canis lupus familiaris \u00b7 TAX_9615

assertion_type:
variant_call
trust_layer:
source_fact
assertions:
234
sources:
2

The OpenBio Demo Corpus

Five organisms. One evidence substrate.

  1. James Morrison, 58

    Homo sapiens · Human oncology

    847

    assertions

  2. Luna

    Canis lupus familiaris · Canine patient

    234

    assertions

  3. M-4872

    Macaca mulatta · Research primate

    512

    assertions

  4. HeLa-S3

    Homo sapiens (derived) · Cell line

    1,247

    passages

  5. E. coli K-12 MG1655

    Escherichia coli · Microbial strain

    4,891

    features

Explore cross-species evidence.